Cargando…
TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis
Compartmentalization of Toll-like receptors (TLRs) in intestinal epithelial cells (IECs) regulates distinct immune responses to microbes; however, the specific cellular machinery that controls this mechanism has not been fully identified. Here we provide genetic evidences that the recycling endosoma...
Autores principales: | Yu, Shiyan, Nie, Yingchao, Knowles, Byron, Sakamori, Ryotaro, Stypulkowski, Ewa, Patel, Chirag, Das, Soumyashree, Douard, Veronique, Ferraris, Ronaldo P, Bonder, Edward M, Goldenring, James R, Ip, Yicktung Tony, Gao, Nan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195784/ https://www.ncbi.nlm.nih.gov/pubmed/25063677 http://dx.doi.org/10.15252/embj.201487888 |
Ejemplares similares
-
Rab8 attenuates Wnt signaling and is required for mesenchymal differentiation into adipocytes
por: Stypulkowski, Ewa, et al.
Publicado: (2021) -
Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche
por: Das, Soumyashree, et al.
Publicado: (2015) -
Rab7 Associates with Early Endosomes to Mediate Sorting and Transport of Semliki Forest Virus to Late Endosomes
por: Vonderheit, Andreas, et al.
Publicado: (2005) -
Rab4A organizes endosomal domains for sorting cargo to lysosome-related organelles
por: Nag, Sudeshna, et al.
Publicado: (2018) -
Rab25 regulates integrin expression in polarized colonic epithelial cells
por: Krishnan, Moorthy, et al.
Publicado: (2013)