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Role of gamma-secretase in human umbilical-cord derived mesenchymal stem cell mediated suppression of NK cell cytotoxicity

BACKGROUND: Mesenchymal stem cells (MSCs) are increasingly considered to be used as biological immunosuppressants in hematopoietic stem cell transplantation (HSCT). In the early reconstitution phase following HSCT, natural killer (NK) cells represent the major lymphocyte population in peripheral blo...

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Detalles Bibliográficos
Autores principales: Chatterjee, Debanjana, Marquardt, Nicole, Tufa, Dejene Milkessa, Beauclair, Guillaume, Low, Hui Zhi, Hatlapatka, Tim, Hass, Ralf, Kasper, Cornelia, von Kaisenberg, Constantin, Schmidt, Reinhold Ernst, Jacobs, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195898/
https://www.ncbi.nlm.nih.gov/pubmed/25266361
http://dx.doi.org/10.1186/s12964-014-0063-9