Cargando…

BDNF-TrkB signaling through Erk1/2(MAPK) phosphorylation mediates the enhancement of fear memory induced by glucocorticoids

Activation of glucocorticoid receptors (GR) by glucocorticoid hormones (GC) enhances contextual fear memories through the activation of the Erk1/2(MAPK) signaling pathway. However, the molecular mechanism mediating this effect of GC remains unknown. Here we used complementary molecular and behaviora...

Descripción completa

Detalles Bibliográficos
Autores principales: Revest, J-M, Le Roux, A, Roullot-Lacarrière, V, Kaouane, N, Vallée, M, Kasanetz, F, Rougé-Pont, F, Tronche, F, Desmedt, A, Piazza, P V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195976/
https://www.ncbi.nlm.nih.gov/pubmed/24126929
http://dx.doi.org/10.1038/mp.2013.134