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Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells

In this study, we attempted to develop a multimodality approach using chemotherapeutic agent mitomycin C, biologic agent tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo-2L), and mild hyperthermia to treat colon cancer. For this study, human colon cancer LS174T, LS180, HCT116 and C...

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Detalles Bibliográficos
Autores principales:	Kim, Seog-Young, Lee, Dae-Hee, Song, Xinxin, Bartlett, David L., Kwon, Yong Tae, Lee, Yong J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2014
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196052/ https://www.ncbi.nlm.nih.gov/pubmed/25156145 http://dx.doi.org/10.1007/s10495-014-1028-6

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