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In situ drug-receptor binding kinetics in single cells: a quantitative label-free study of anti-tumor drug resistance
Many drugs are effective in the early stage of treatment, but patients develop drug resistance after a certain period of treatment, causing failure of the therapy. An important example is Herceptin, a popular monoclonal antibody drug for breast cancer by specifically targeting human epidermal growth...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196117/ https://www.ncbi.nlm.nih.gov/pubmed/25312029 http://dx.doi.org/10.1038/srep06609 |