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The GC + CC genotype at position -418 in TIMP-2 promoter and the -1575GA/-1306CC genotype in MMP-2 is genetic predisposing factors for prevalence of moyamoya disease

BACKGROUND: To investigate the association of single-nucleotide polymorphisms (SNPs) in matrix metalloproteinases (MMPs)-2, -3, and -9 and tissue inhibitor of metalloproteinase (TIMP)-2 with moyamoya disease (MMD). We conducted a case-control study of MMD patients by assessing the prevalence of six...

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Detalles Bibliográficos
Autores principales: Park, Young Seok, Jeon, Young Joo, Kim, Hyun Seok, Han, In Bo, Oh, Seung-Hun, Kim, Dong-Seok, Kim, Nam Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196131/
https://www.ncbi.nlm.nih.gov/pubmed/25280484
http://dx.doi.org/10.1186/s12883-014-0180-5

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