HDAC inhibitors and immunotherapy; a double edged sword?

Epigenetic modifications, like histone acetylation, are essential for regulating gene expression within cells. Cancer cells acquire pathological epigenetic modifications resulting in gene expression patterns that facilitate and sustain tumorigenesis. Epigenetic manipulation therefore is emerging as...

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Detalles Bibliográficos
Autores principales: Kroesen, Michiel, Gielen, Paul, Brok, Ingrid C., Armandari, Inna, Hoogerbrugge, Peter M., Adema, Gosse J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196144/
https://www.ncbi.nlm.nih.gov/pubmed/25115382

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