Ablation of EIF5A2 induces tumor vasculature remodeling and improves tumor response to chemotherapy via regulation of matrix metalloproteinase 2 expression

Hepatocellular carcinoma (HCC) is a highly vascularized tumor with poor clinical outcome. Our previous work has shown that eukaryotic initiation factor 5A2 (EIF5A2) over-expression enhances HCC cell metastasis. In this study, EIF5A2 was identified to be an independent risk factor for poor disease-sp...

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Detalles Bibliográficos
Autores principales: Wang, Feng-Wei, Cai, Mu-Yan, Mai, Shi-Juan, Chen, Jie-Wei, Bai, Hai-Yan, Li, Yan, Liao, Yi-Ji, Li, Chang-Peng, Tian, Xiao-Peng, Kung, Hsiang-Fu, Guan, Xin-Yuan, Xie, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196158/
https://www.ncbi.nlm.nih.gov/pubmed/25071013

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