The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis

The majority of human breast cancers express estrogen receptor alpha (ER), which is important for therapy with anti-estrogens. Here we describe the role of BCL9-2, a proto-oncogene previously characterized as co-activator of Wnt/ß-catenin signaling, for mammary tumorigenesis in mice and human. ER po...

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Detalles Bibliográficos
Autores principales: Zatula, Nathalie, Wiese, Maria, Bunzendahl, Jens, Birchmeier, Walter, Perske, Christina, Bleckmann, Annalen, Brembeck, Felix H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196162/
https://www.ncbi.nlm.nih.gov/pubmed/25149534

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