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A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling

BACKGROUND: Temporal and local fluctuations in O(2) in tumors require adaptive mechanisms to support cancer cell survival and proliferation. The transcriptome associated with cycling hypoxia (CycHyp) could thus represent a prognostic biomarker of cancer progression. METHODS: We exposed 20 tumor cell...

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Detalles Bibliográficos
Autores principales: Boidot, Romain, Branders, Samuel, Helleputte, Thibault, Rubio, Laila Illan, Dupont, Pierre, Feron, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196175/
https://www.ncbi.nlm.nih.gov/pubmed/25216520