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Secreted frizzled related proteins inhibit fibrosis in vitro but appear redundant in vivo
BACKGROUND: The pathogenesis of pulmonary fibrosis remains poorly understood. The Wnt signaling pathway regulates fibrogenesis in different organs. Here, we studied the role of two extracellular Wnt antagonists, secreted frizzled-related protein-1 (SFRP1) and frizzled-related protein (FRZB) on lung...
Autores principales: | De Langhe, Ellen, Aznar-Lopez, Carolina, De Vooght, Vanessa, Vanoirbeek, Jeroen A, Luyten, Frank P, Lories, Rik JU |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196208/ https://www.ncbi.nlm.nih.gov/pubmed/25317206 http://dx.doi.org/10.1186/1755-1536-7-14 |
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