LpxC Inhibitors as New Antibacterial Agents and Tools for Studying Regulation of Lipid A Biosynthesis in Gram-Negative Pathogens

The problem of multidrug resistance in serious Gram-negative bacterial pathogens has escalated so severely that new cellular targets and pathways need to be exploited to avoid many of the preexisting antibiotic resistance mechanisms that are rapidly disseminating to new strains. The discovery of sma...

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Detalles Bibliográficos
Autores principales: Tomaras, Andrew P., McPherson, Craig J., Kuhn, Michael, Carifa, Arlene, Mullins, Lisa, George, David, Desbonnet, Charlene, Eidem, Tess M., Montgomery, Justin I., Brown, Matthew F., Reilly, Usa, Miller, Alita A., O’Donnell, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196226/
https://www.ncbi.nlm.nih.gov/pubmed/25271285
http://dx.doi.org/10.1128/mBio.01551-14

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