MicroRNAs - Biology and clinical applications

MicroRNAs are a highly conserved group of small, non-coding RNA molecules, which are 19-25 nucleotides in size. Previously thought to be evolutionary debris with no evident function, these small RNAs have been found to control gene expression primarily by silencing the gene. MicroRNAs are critical t...

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Detalles Bibliográficos
Autores principales: Ranganathan, Kannan, Sivasankar, Vaishnavi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196292/
https://www.ncbi.nlm.nih.gov/pubmed/25328304
http://dx.doi.org/10.4103/0973-029X.140762
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author Ranganathan, Kannan
Sivasankar, Vaishnavi
author_facet Ranganathan, Kannan
Sivasankar, Vaishnavi
author_sort Ranganathan, Kannan
collection PubMed
description MicroRNAs are a highly conserved group of small, non-coding RNA molecules, which are 19-25 nucleotides in size. Previously thought to be evolutionary debris with no evident function, these small RNAs have been found to control gene expression primarily by silencing the gene. MicroRNAs are critical to cell physiology and development. They are also implicated in pathological processes such as autoimmune diseases, viral infections and carcinogenesis.
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spelling pubmed-41962922014-10-17 MicroRNAs - Biology and clinical applications Ranganathan, Kannan Sivasankar, Vaishnavi J Oral Maxillofac Pathol Review Article MicroRNAs are a highly conserved group of small, non-coding RNA molecules, which are 19-25 nucleotides in size. Previously thought to be evolutionary debris with no evident function, these small RNAs have been found to control gene expression primarily by silencing the gene. MicroRNAs are critical to cell physiology and development. They are also implicated in pathological processes such as autoimmune diseases, viral infections and carcinogenesis. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4196292/ /pubmed/25328304 http://dx.doi.org/10.4103/0973-029X.140762 Text en Copyright: © Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ranganathan, Kannan
Sivasankar, Vaishnavi
MicroRNAs - Biology and clinical applications
title MicroRNAs - Biology and clinical applications
title_full MicroRNAs - Biology and clinical applications
title_fullStr MicroRNAs - Biology and clinical applications
title_full_unstemmed MicroRNAs - Biology and clinical applications
title_short MicroRNAs - Biology and clinical applications
title_sort micrornas - biology and clinical applications
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196292/
https://www.ncbi.nlm.nih.gov/pubmed/25328304
http://dx.doi.org/10.4103/0973-029X.140762
work_keys_str_mv AT ranganathankannan micrornasbiologyandclinicalapplications
AT sivasankarvaishnavi micrornasbiologyandclinicalapplications

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