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Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial
INTRODUCTION: Antibiotic therapy before or after orthognathic surgery is commonly recommended by surgeons to minimize the risk of wound infection. This article evaluates the value of Prophylactic antibiotic therapy in order to diminish the incidence of postoperative wound infection after orthognathi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196443/ https://www.ncbi.nlm.nih.gov/pubmed/25320697 |
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author | Eshghpour, Majid Khajavi, Amin Bagheri, Mahmoud Banihashemi, Elham |
author_facet | Eshghpour, Majid Khajavi, Amin Bagheri, Mahmoud Banihashemi, Elham |
author_sort | Eshghpour, Majid |
collection | PubMed |
description | INTRODUCTION: Antibiotic therapy before or after orthognathic surgery is commonly recommended by surgeons to minimize the risk of wound infection. This article evaluates the value of Prophylactic antibiotic therapy in order to diminish the incidence of postoperative wound infection after orthognathic surgery. MATERIALS AND METHODS: Fifty candidates for bimaxillary orthognathic surgery were divided into cases and controls. Cefazolin (1g) was administered intravenously to all participants 30 mins prior to surgery followed by a similar dose 4 hours later. Case-group patients ingested amoxicillin (500 mg) orally for 7 days after surgery. Postoperative wound infection was assessed using clinical features, and the P-value significance was set at P<0.05. RESULTS: Both groups were similar according to gender, age, and operating time. During the follow-up period no infection was observed in either the case or control group. CONCLUSION: The results of this study suggest that long-term postoperative antibiotic therapy is not essential for the prevention of postoperative infection, and that application of aseptic surgical technique and hygiene instruction after surgery are sufficient. |
format | Online Article Text |
id | pubmed-4196443 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Mashhad University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-41964432014-10-15 Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial Eshghpour, Majid Khajavi, Amin Bagheri, Mahmoud Banihashemi, Elham Iran J Otorhinolaryngol Original Article INTRODUCTION: Antibiotic therapy before or after orthognathic surgery is commonly recommended by surgeons to minimize the risk of wound infection. This article evaluates the value of Prophylactic antibiotic therapy in order to diminish the incidence of postoperative wound infection after orthognathic surgery. MATERIALS AND METHODS: Fifty candidates for bimaxillary orthognathic surgery were divided into cases and controls. Cefazolin (1g) was administered intravenously to all participants 30 mins prior to surgery followed by a similar dose 4 hours later. Case-group patients ingested amoxicillin (500 mg) orally for 7 days after surgery. Postoperative wound infection was assessed using clinical features, and the P-value significance was set at P<0.05. RESULTS: Both groups were similar according to gender, age, and operating time. During the follow-up period no infection was observed in either the case or control group. CONCLUSION: The results of this study suggest that long-term postoperative antibiotic therapy is not essential for the prevention of postoperative infection, and that application of aseptic surgical technique and hygiene instruction after surgery are sufficient. Mashhad University of Medical Sciences 2014-10 /pmc/articles/PMC4196443/ /pubmed/25320697 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Eshghpour, Majid Khajavi, Amin Bagheri, Mahmoud Banihashemi, Elham Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial |
title | Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial |
title_full | Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial |
title_fullStr | Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial |
title_full_unstemmed | Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial |
title_short | Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial |
title_sort | value of prophylactic postoperative antibiotic therapy after bimaxillary orthognathic surgery: a clinical trial |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196443/ https://www.ncbi.nlm.nih.gov/pubmed/25320697 |
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