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Pharmacogenomics of acetaminophen in pediatric populations: a moving target

Acetaminophen (APAP) is widely used as an over-the-counter fever reducer and pain reliever. However, the current therapeutic use of APAP is not optimal. The inter-patient variability in both efficacy and toxicity limits the use of this drug. This is particularly an issue in pediatric populations, wh...

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Detalles Bibliográficos
Autores principales: Krasniak, Anne E., Knipp, Gregory T., Svensson, Craig K., Liu, Wanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196544/
https://www.ncbi.nlm.nih.gov/pubmed/25352860
http://dx.doi.org/10.3389/fgene.2014.00314