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Expansion of CAG Repeats in Escherichia coli Is Controlled by Single-Strand DNA Exonucleases of Both Polarities

The expansion of CAG·CTG repeat tracts is responsible for several neurodegenerative diseases, including Huntington disease and myotonic dystrophy. Understanding the molecular mechanism of CAG·CTG repeat tract expansion is therefore important if we are to develop medical interventions limiting expans...

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Detalles Bibliográficos
Autores principales:	Jackson, Adam, Okely, Ewa A., Leach, David R. F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2014
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196609/ https://www.ncbi.nlm.nih.gov/pubmed/25081568 http://dx.doi.org/10.1534/genetics.114.168245

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