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HBP1 promoter methylation augments the oncogenic β-catenin to correlate with prognosis in NSCLC

β-catenin nuclear accumulation is frequently identified in human non-small cell lung cancer (NSCLC). The HMG-box transcription factor 1 (HBP1) is a known repressor of β-catenin transactivation. However, the role of HBP1 in relation to β-catenin nuclear accumulation has not been addressed in human ca...

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Detalles Bibliográficos
Autores principales: Tseng, Ruo-Chia, Huang, Way-Ren, Lin, Su-Feng, Wu, Pei-Chen, Hsu, Han-Shui, Wang, Yi-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196651/
https://www.ncbi.nlm.nih.gov/pubmed/24895061
http://dx.doi.org/10.1111/jcmm.12318