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Autophagy and Its Effects: Making Sense of Double-Edged Swords

Autophagy delivers cellular material to lysosomes for recycling. This article discusses why both good and bad effects arise because of autophagy and argues that exploiting this knowledge can treat disease.

Detalles Bibliográficos
Autor principal: Thorburn, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196727/
https://www.ncbi.nlm.nih.gov/pubmed/25313680
http://dx.doi.org/10.1371/journal.pbio.1001967
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author Thorburn, Andrew
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description Autophagy delivers cellular material to lysosomes for recycling. This article discusses why both good and bad effects arise because of autophagy and argues that exploiting this knowledge can treat disease.
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spelling pubmed-41967272014-10-16 Autophagy and Its Effects: Making Sense of Double-Edged Swords Thorburn, Andrew PLoS Biol Essay Autophagy delivers cellular material to lysosomes for recycling. This article discusses why both good and bad effects arise because of autophagy and argues that exploiting this knowledge can treat disease. Public Library of Science 2014-10-14 /pmc/articles/PMC4196727/ /pubmed/25313680 http://dx.doi.org/10.1371/journal.pbio.1001967 Text en © 2014 Andrew Thorburn http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Essay
Thorburn, Andrew
Autophagy and Its Effects: Making Sense of Double-Edged Swords
title Autophagy and Its Effects: Making Sense of Double-Edged Swords
title_full Autophagy and Its Effects: Making Sense of Double-Edged Swords
title_fullStr Autophagy and Its Effects: Making Sense of Double-Edged Swords
title_full_unstemmed Autophagy and Its Effects: Making Sense of Double-Edged Swords
title_short Autophagy and Its Effects: Making Sense of Double-Edged Swords
title_sort autophagy and its effects: making sense of double-edged swords
topic Essay
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196727/
https://www.ncbi.nlm.nih.gov/pubmed/25313680
http://dx.doi.org/10.1371/journal.pbio.1001967
work_keys_str_mv AT thorburnandrew autophagyanditseffectsmakingsenseofdoubleedgedswords