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Melanoma Cells Break Down LPA to Establish Local Gradients That Drive Chemotactic Dispersal

The high mortality of melanoma is caused by rapid spread of cancer cells, which occurs unusually early in tumour evolution. Unlike most solid tumours, thickness rather than cytological markers or differentiation is the best guide to metastatic potential. Multiple stimuli that drive melanoma cell mig...

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Detalles Bibliográficos
Autores principales: Muinonen-Martin, Andrew J., Susanto, Olivia, Zhang, Qifeng, Smethurst, Elizabeth, Faller, William J., Veltman, Douwe M., Kalna, Gabriela, Lindsay, Colin, Bennett, Dorothy C., Sansom, Owen J., Herd, Robert, Jones, Robert, Machesky, Laura M., Wakelam, Michael J. O., Knecht, David A., Insall, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196730/
https://www.ncbi.nlm.nih.gov/pubmed/25313567
http://dx.doi.org/10.1371/journal.pbio.1001966