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Melanoma Cells Break Down LPA to Establish Local Gradients That Drive Chemotactic Dispersal
The high mortality of melanoma is caused by rapid spread of cancer cells, which occurs unusually early in tumour evolution. Unlike most solid tumours, thickness rather than cytological markers or differentiation is the best guide to metastatic potential. Multiple stimuli that drive melanoma cell mig...
Autores principales: | Muinonen-Martin, Andrew J., Susanto, Olivia, Zhang, Qifeng, Smethurst, Elizabeth, Faller, William J., Veltman, Douwe M., Kalna, Gabriela, Lindsay, Colin, Bennett, Dorothy C., Sansom, Owen J., Herd, Robert, Jones, Robert, Machesky, Laura M., Wakelam, Michael J. O., Knecht, David A., Insall, Robert H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196730/ https://www.ncbi.nlm.nih.gov/pubmed/25313567 http://dx.doi.org/10.1371/journal.pbio.1001966 |
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