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A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria
Mitochondrial membrane biogenesis and lipid metabolism require phospholipid transfer from the endoplasmic reticulum (ER) to mitochondria. Transfer is thought to occur at regions of close contact of these organelles and to be nonvesicular, but the mechanism is not known. Here we used a novel genetic...
Autores principales: | Lahiri, Sujoy, Chao, Jesse T., Tavassoli, Shabnam, Wong, Andrew K. O., Choudhary, Vineet, Young, Barry P., Loewen, Christopher J. R., Prinz, William A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196738/ https://www.ncbi.nlm.nih.gov/pubmed/25313861 http://dx.doi.org/10.1371/journal.pbio.1001969 |
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