The Chromatin Assembly Factor 1 Promotes Rad51-Dependent Template Switches at Replication Forks by Counteracting D-Loop Disassembly by the RecQ-Type Helicase Rqh1

At blocked replication forks, homologous recombination mediates the nascent strands to switch template in order to ensure replication restart, but faulty template switches underlie genome rearrangements in cancer cells and genomic disorders. Recombination occurs within DNA packaged into chromatin th...

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Detalles Bibliográficos
Autores principales: Pietrobon, Violena, Fréon, Karine, Hardy, Julien, Costes, Audrey, Iraqui, Ismail, Ochsenbein, Françoise, Lambert, Sarah A.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196752/
https://www.ncbi.nlm.nih.gov/pubmed/25313826
http://dx.doi.org/10.1371/journal.pbio.1001968

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