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Extreme High Prevalence of a Defective Mannose-Binding Lectin (MBL2) Genotype in Native South American West Andean Populations

Mannose-binding lectin (MBL) is one of the five recognition molecules in the lectin complement pathway. Common variant alleles in the promoter and structural regions of the human MBL gene (MBL2) influence the stability and serum concentration of the protein. Epidemiological studies have shown that M...

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Detalles Bibliográficos
Autores principales: Sandoval, José Raul, Madsen, Hans O., De Stefano, Gianfranco, Descailleaux-Dulanto, Jaime, Velazquez-Reinoso, Margarita, Ñique, Cesar, Fujita, Ricardo, Garred, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196846/
https://www.ncbi.nlm.nih.gov/pubmed/25313559
http://dx.doi.org/10.1371/journal.pone.0108943