Structural Characteristic of the Initial Unfolded State on Refolding Determines Catalytic Efficiency of the Folded Protein in Presence of Osmolytes

Osmolytes are low molecular weight organic molecules accumulated by organisms to assist proper protein folding, and to provide protection to the structural integrity of proteins under denaturing stress conditions. It is known that osmolyte-induced protein folding is brought by unfavorable interactio...

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Detalles Bibliográficos
Autores principales: Warepam, Marina, Sharma, Gurumayum Suraj, Dar, Tanveer Ali, Khan, Md. Khurshid Alam, Singh, Laishram Rajendrakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196897/
https://www.ncbi.nlm.nih.gov/pubmed/25313668
http://dx.doi.org/10.1371/journal.pone.0109408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196897/
https://www.ncbi.nlm.nih.gov/pubmed/25313668
http://dx.doi.org/10.1371/journal.pone.0109408

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