Enhanced Cytotoxicity of Natural Killer Cells following the Acquisition of Chimeric Antigen Receptors through Trogocytosis

Natural killer (NK) cells have the capacity to target tumors and are ideal candidates for immunotherapy. Viral vectors have been used to genetically modify in vitro expanded NK cells to express chimeric antigen receptors (CARs), which confer cytotoxicity against tumors. However, use of viral transdu...

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Detalles Bibliográficos
Autores principales: Cho, Fu-Nan, Chang, Tsung-Hsien, Shu, Chih-Wen, Ko, Ming-Chin, Liao, Shuen-Kuei, Wu, Kang-Hsi, Yu, Ming-Sun, Lin, Shyh-Jer, Hong, Ying-Chung, Chen, Chien-Hsun, Hung, Chien-Hui, Chang, Yu-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196898/
https://www.ncbi.nlm.nih.gov/pubmed/25313995
http://dx.doi.org/10.1371/journal.pone.0109352

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