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Group VIB Calcium-Independent Phospholipase A(2) (iPLA(2)γ) Regulates Platelet Activation, Hemostasis and Thrombosis in Mice
In platelets, group IVA cytosolic phospholipase A(2) (cPLA(2)α) has been implicated as a key regulator in the hydrolysis of platelet membrane phospholipids, leading to pro-thrombotic thromboxane A(2) and anti-thrombotic 12-(S)-hydroxyeicosatetranoic acid production. However, studies using cPLA(2)α-d...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196902/ https://www.ncbi.nlm.nih.gov/pubmed/25313821 http://dx.doi.org/10.1371/journal.pone.0109409 |