Pyrroloquinoline Quinone (PQQ) Inhibits Lipopolysaccharide Induced Inflammation in Part via Downregulated NF-κB and p38/JNK Activation in Microglial and Attenuates Microglia Activation in Lipopolysaccharide Treatment Mice

Therapeutic strategies designed to inhibit the activation of microglia may lead to significant advancement in the treatment of most neurodegenerative diseases. Pyrroloquinoline quinone (PQQ) is a naturally occurring redox cofactor that acts as an essential nutrient, antioxidant, and has been reporte...

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Detalles Bibliográficos
Autores principales: Yang, Chongfei, Yu, Lifeng, Kong, Lingbo, Ma, Rui, Zhang, Juliang, Zhu, Qingsheng, Zhu, Jinyu, Hao, Dingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196908/
https://www.ncbi.nlm.nih.gov/pubmed/25314304
http://dx.doi.org/10.1371/journal.pone.0109502

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