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Gli1 Haploinsufficiency Leads to Decreased Bone Mass with an Uncoupling of Bone Metabolism in Adult Mice

Hedgehog (Hh) signaling plays important roles in various development processes. This signaling is necessary for osteoblast formation during endochondral ossification. In contrast to the established roles of Hh signaling in embryonic bone formation, evidence of its roles in adult bone homeostasis is...

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Detalles Bibliográficos
Autores principales:	Kitaura, Yoshiaki, Hojo, Hironori, Komiyama, Yuske, Takato, Tsuyoshi, Chung, Ung-il, Ohba, Shinsuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196929/ https://www.ncbi.nlm.nih.gov/pubmed/25313900 http://dx.doi.org/10.1371/journal.pone.0109597

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