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A Novel Model of Chronic Wounds: Importance of Redox Imbalance and Biofilm-Forming Bacteria for Establishment of Chronicity
Chronic wounds have a large impact on health, affecting ∼6.5 M people and costing ∼$25B/year in the US alone [1]. We previously discovered that a genetically modified mouse model displays impaired healing similar to problematic wounds in humans and that sometimes the wounds become chronic. Here we s...
Autores principales: | Dhall, Sandeep, Do, Danh, Garcia, Monika, Wijesinghe, Dayanjan Shanaka, Brandon, Angela, Kim, Jane, Sanchez, Antonio, Lyubovitsky, Julia, Gallagher, Sean, Nothnagel, Eugene A., Chalfant, Charles E., Patel, Rakesh P., Schiller, Neal, Martins-Green, Manuela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196950/ https://www.ncbi.nlm.nih.gov/pubmed/25313558 http://dx.doi.org/10.1371/journal.pone.0109848 |
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