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TP53 Mutational Status Is a Potential Marker for Risk Stratification in Wilms Tumour with Diffuse Anaplasia
PURPOSE: The presence of diffuse anaplasia in Wilms tumours (DAWT) is associated with TP53 mutations and poor outcome. As patients receive intensified treatment, we sought to identify whether TP53 mutational status confers additional prognostic information. PATIENTS AND METHODS: We studied 40 patien...
Autores principales: | Maschietto, Mariana, Williams, Richard D., Chagtai, Tasnim, Popov, Sergey D., Sebire, Neil J., Vujanic, Gordan, Perlman, Elizabeth, Anderson, James R., Grundy, Paul, Dome, Jeffrey S., Pritchard-Jones, Kathy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196953/ https://www.ncbi.nlm.nih.gov/pubmed/25313908 http://dx.doi.org/10.1371/journal.pone.0109924 |
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