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Glucocorticoids synergize with IL-1β to induce TLR2 expression via MAP Kinase Phosphatase-1-dependent dual Inhibition of MAPK JNK and p38 in epithelial cells

BACKGROUND: Despite the importance of glucocorticoids in suppressing immune and inflammatory responses, their role in enhancing host immune and defense response against invading bacteria is poorly understood. Toll-like receptor 2 (TLR2) has recently gained importance as one of the major host defense...

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Detalles Bibliográficos
Autores principales: Sakai, Akihiro, Han, Jiahuai, Cato, Andrew CB, Akira, Shizuo, Li, Jian-Dong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419700/
https://www.ncbi.nlm.nih.gov/pubmed/15125785
http://dx.doi.org/10.1186/1471-2199-5-2