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Glucocorticoids synergize with IL-1β to induce TLR2 expression via MAP Kinase Phosphatase-1-dependent dual Inhibition of MAPK JNK and p38 in epithelial cells
BACKGROUND: Despite the importance of glucocorticoids in suppressing immune and inflammatory responses, their role in enhancing host immune and defense response against invading bacteria is poorly understood. Toll-like receptor 2 (TLR2) has recently gained importance as one of the major host defense...
Autores principales: | Sakai, Akihiro, Han, Jiahuai, Cato, Andrew CB, Akira, Shizuo, Li, Jian-Dong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419700/ https://www.ncbi.nlm.nih.gov/pubmed/15125785 http://dx.doi.org/10.1186/1471-2199-5-2 |
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