Epigenetic CRBP downregulation appears to be an evolutionarily conserved (human and mouse) and oncogene-specific phenomenon in breast cancer

BACKGROUND: The cellular retinol binding protein I gene (CRBP) is downregulated in a subset of human breast cancers and in MMTV-Myc induced mouse mammary tumors. Functional studies suggest that CRBP downregulation contributes to breast tumor progression. What is the mechanism underlying CRBP downreg...

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Detalles Bibliográficos
Autores principales: Arapshian, Alice, Bertran, Silvina, Kuppumbatti, Yuvarani S, Nakajo, Shigeo, Mira-y-Lopez, Rafael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC419713/
https://www.ncbi.nlm.nih.gov/pubmed/15113415
http://dx.doi.org/10.1186/1476-4598-3-13

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