Association between acquired resistance to PLX4032 (vemurafenib) and ATP-binding cassette transporter expression

BACKGROUND: Various kinase inhibitors are known to be ATP-binding cassette (ABC) transporter substrates and resistance acquisition to kinase inhibitors has been associated to increased ABC transporter expression. Here, we investigated the role of the ABC transporters ABCB1, ABCC1, and ABCG2 during m...

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Detalles Bibliográficos
Autores principales: Michaelis, Martin, Rothweiler, Florian, Nerreter, Thomas, van Rikxoort, Marijke, Zehner, Richard, Dirks, Wilhelm G, Wiese, Michael, Cinatl, Jindrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197243/
https://www.ncbi.nlm.nih.gov/pubmed/25300205
http://dx.doi.org/10.1186/1756-0500-7-710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197243/
https://www.ncbi.nlm.nih.gov/pubmed/25300205
http://dx.doi.org/10.1186/1756-0500-7-710

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