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Catechins induced acute promyelocytic leukemia cell apoptosis and triggered PML-RARα oncoprotein degradation

BACKGROUND: It has recently been reported that the extracts of green tea polyphenol have cancer preventive effects. In this study, we investigated the effect of the natural composition from green tea leaves Catechins on acute promyelocytic leukemia (APL). METHODS: In vitro, APL cell lines NB4, retin...

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Detalles Bibliográficos
Autores principales:	Zhang, Li, Chen, Qiu-Sheng, Xu, Peng-Peng, Qian, Ying, Wang, Ai-Hua, Xiao, Dan, Zhao, Yan, Sheng, Yan, Wen, Xiang-Qin, Zhao, Wei-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197244/ https://www.ncbi.nlm.nih.gov/pubmed/25270015 http://dx.doi.org/10.1186/s13045-014-0075-3

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