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Agonist activation of estrogen receptor beta (ERβ) sensitizes malignant pleural mesothelioma cells to cisplatin cytotoxicity

BACKGROUND: Estrogen receptor (ER) β acts as a tumor suppressor in malignant mesotheliomas. METHODS: Here we explored the anti-proliferative and anti-tumorigenic efficacy of the selective ERβ agonist, KB9520, in human mesothelioma cell lines in vitro and in a mesothelioma mouse model in vivo. RESULT...

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Detalles Bibliográficos
Autores principales:	Pinton, Giulia, Manente, Arcangela G, Daga, Antonio, Cilli, Michele, Rinaldi, Maurizio, Nilsson, Stefan, Moro, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197308/ https://www.ncbi.nlm.nih.gov/pubmed/25277603 http://dx.doi.org/10.1186/1476-4598-13-227

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