Cargando…
Verbascoside promotes apoptosis by regulating HIPK2–p53 signaling in human colorectal cancer
BACKGROUND: We investigated the role of the HIPK2–p53 signaling pathway in tumorigenesis and resistance to the drug Verbascoside (VB) in colorectal cancer (CRC), using in vivo and in vitro experiments. METHODS: Primary human CRC samples and normal intestinal tissues from patients were analyzed for H...
Autores principales: | Zhou, Lihong, Feng, Yuanyuan, Jin, Yongjie, Liu, Xuan, Sui, Hua, Chai, Ni, Chen, Xingzhu, Liu, Ningning, Ji, Qing, Wang, Yan, Li, Qi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197337/ https://www.ncbi.nlm.nih.gov/pubmed/25282590 http://dx.doi.org/10.1186/1471-2407-14-747 |
Ejemplares similares
-
Verbascoside promotes the regeneration of tyrosine hydroxylase-immunoreactive neurons in the substantia nigra
por: Liang, Jian-qing, et al.
Publicado: (2016) -
Complete biosynthesis of the phenylethanoid glycoside verbascoside
por: Yang, Yihan, et al.
Publicado: (2023) -
JianPi JieDu Recipe Inhibits Epithelial-to-Mesenchymal Transition in Colorectal Cancer through TGF-β/Smad Mediated Snail/E-Cadherin Expression
por: Liu, Xuan, et al.
Publicado: (2017) -
HIF-1α antagonizes p53-mediated apoptosis by triggering HIPK2 degradation
por: Nardinocchi, Lavinia, et al.
Publicado: (2011) -
Homeodomain-interacting protein kinase 2 (HIPK2): a promising target for anti-cancer therapies
por: Feng, Yuanyuan, et al.
Publicado: (2017)