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Cutaneous leiomyosarcoma – Case report
Abstract Cutaneous leiomyosarcoma (CLM) is a very rare smooth muscle tumor arising from the dermis or subcutaneous tissue in the skin. Superficial leiomyosarcoma originates in the superficial dermis or subcutaneous tissue and represents about 3% of the soft tissue sarcomas. CLM presents in persons o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Carol Davila University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197510/ https://www.ncbi.nlm.nih.gov/pubmed/25408738 |
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author | Ciurea, ME Georgescu, CV Radu, CC Georgescu, CC Stoica, LE |
author_facet | Ciurea, ME Georgescu, CV Radu, CC Georgescu, CC Stoica, LE |
author_sort | Ciurea, ME |
collection | PubMed |
description | Abstract Cutaneous leiomyosarcoma (CLM) is a very rare smooth muscle tumor arising from the dermis or subcutaneous tissue in the skin. Superficial leiomyosarcoma originates in the superficial dermis or subcutaneous tissue and represents about 3% of the soft tissue sarcomas. CLM presents in persons of all ages but with a peak between 60-70 years old. It may also occur anywhere on the body; the existing cases reported it on the face and trunk. The clinic of leiomyosarcoma consists in a firm dermal nodule, which can be painful, pruritic or paresthestic. The tumor is of 1-3 cm in diameter and can often be seen as a solitary formation. We report one case of a cutaneous leiomyosarcoma arising in the chest region of a 79- year-old male. Leiomyosarcoma is a rare entity whose clinical presentation may appear nonspecific, making diagnosis difficult. Primary tumor excision with wide oncological safety margins is considered, when suitable case, the most appropriate method. Other therapeutic methods, such as radio- or chemotherapy are described as without significant benefits. Despite the claims of radical surgical treatment, due to recurrence rates, the prognosis remains poor. We recommend long-term follow-up of patients to capture a subsequent malignant disease progression. |
format | Online Article Text |
id | pubmed-4197510 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Carol Davila University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-41975102014-11-18 Cutaneous leiomyosarcoma – Case report Ciurea, ME Georgescu, CV Radu, CC Georgescu, CC Stoica, LE J Med Life Case Presentation Abstract Cutaneous leiomyosarcoma (CLM) is a very rare smooth muscle tumor arising from the dermis or subcutaneous tissue in the skin. Superficial leiomyosarcoma originates in the superficial dermis or subcutaneous tissue and represents about 3% of the soft tissue sarcomas. CLM presents in persons of all ages but with a peak between 60-70 years old. It may also occur anywhere on the body; the existing cases reported it on the face and trunk. The clinic of leiomyosarcoma consists in a firm dermal nodule, which can be painful, pruritic or paresthestic. The tumor is of 1-3 cm in diameter and can often be seen as a solitary formation. We report one case of a cutaneous leiomyosarcoma arising in the chest region of a 79- year-old male. Leiomyosarcoma is a rare entity whose clinical presentation may appear nonspecific, making diagnosis difficult. Primary tumor excision with wide oncological safety margins is considered, when suitable case, the most appropriate method. Other therapeutic methods, such as radio- or chemotherapy are described as without significant benefits. Despite the claims of radical surgical treatment, due to recurrence rates, the prognosis remains poor. We recommend long-term follow-up of patients to capture a subsequent malignant disease progression. Carol Davila University Press 2014-06-15 2014-06-25 /pmc/articles/PMC4197510/ /pubmed/25408738 Text en ©Carol Davila University Press http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Presentation Ciurea, ME Georgescu, CV Radu, CC Georgescu, CC Stoica, LE Cutaneous leiomyosarcoma – Case report |
title | Cutaneous leiomyosarcoma – Case report |
title_full | Cutaneous leiomyosarcoma – Case report |
title_fullStr | Cutaneous leiomyosarcoma – Case report |
title_full_unstemmed | Cutaneous leiomyosarcoma – Case report |
title_short | Cutaneous leiomyosarcoma – Case report |
title_sort | cutaneous leiomyosarcoma – case report |
topic | Case Presentation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197510/ https://www.ncbi.nlm.nih.gov/pubmed/25408738 |
work_keys_str_mv | AT ciureame cutaneousleiomyosarcomacasereport AT georgescucv cutaneousleiomyosarcomacasereport AT raducc cutaneousleiomyosarcomacasereport AT georgescucc cutaneousleiomyosarcomacasereport AT stoicale cutaneousleiomyosarcomacasereport |