TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy

Low-level laser irradiation in the visible as well as infrared range is applied to skin for treatment of various diseases. Here we summarize and discuss effects of laser irradiation on mast cells that leads to degranulation of the cells. This process may contribute to initial steps in the final medi...

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Detalles Bibliográficos
Autores principales: Wang, Lina, Zhang, Di, Schwarz, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197630/
https://www.ncbi.nlm.nih.gov/pubmed/24971848
http://dx.doi.org/10.3390/cells3030662
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author Wang, Lina
Zhang, Di
Schwarz, Wolfgang
author_facet Wang, Lina
Zhang, Di
Schwarz, Wolfgang
author_sort Wang, Lina
collection PubMed
description Low-level laser irradiation in the visible as well as infrared range is applied to skin for treatment of various diseases. Here we summarize and discuss effects of laser irradiation on mast cells that leads to degranulation of the cells. This process may contribute to initial steps in the final medical effects. We suggest that activation of TRPV channels in the mast cells forms a basis for the underlying mechanisms and that released ATP and histamine may be putative mediators for therapeutic effects.
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spelling pubmed-41976302014-10-16 TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy Wang, Lina Zhang, Di Schwarz, Wolfgang Cells Review Low-level laser irradiation in the visible as well as infrared range is applied to skin for treatment of various diseases. Here we summarize and discuss effects of laser irradiation on mast cells that leads to degranulation of the cells. This process may contribute to initial steps in the final medical effects. We suggest that activation of TRPV channels in the mast cells forms a basis for the underlying mechanisms and that released ATP and histamine may be putative mediators for therapeutic effects. MDPI 2014-06-26 /pmc/articles/PMC4197630/ /pubmed/24971848 http://dx.doi.org/10.3390/cells3030662 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Wang, Lina
Zhang, Di
Schwarz, Wolfgang
TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy
title TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy
title_full TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy
title_fullStr TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy
title_full_unstemmed TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy
title_short TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy
title_sort trpv channels in mast cells as a target for low-level-laser therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197630/
https://www.ncbi.nlm.nih.gov/pubmed/24971848
http://dx.doi.org/10.3390/cells3030662
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AT zhangdi trpvchannelsinmastcellsasatargetforlowlevellasertherapy
AT schwarzwolfgang trpvchannelsinmastcellsasatargetforlowlevellasertherapy

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