Cargando…
Mapping the Shh long-range regulatory domain
Coordinated gene expression controlled by long-distance enhancers is orchestrated by DNA regulatory sequences involving transcription factors and layers of control mechanisms. The Shh gene and well-established regulators are an example of genomic composition in which enhancers reside in a large dese...
Autores principales: | Anderson, Eve, Devenney, Paul S., Hill, Robert E., Lettice, Laura A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197689/ https://www.ncbi.nlm.nih.gov/pubmed/25252942 http://dx.doi.org/10.1242/dev.108480 |
Ejemplares similares
-
A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development
por: Crane-Smith, Zoe, et al.
Publicado: (2021) -
Development of five digits is controlled by a bipartite long-range cis-regulator
por: Lettice, Laura A., et al.
Publicado: (2014) -
Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity
por: Williamson, Iain, et al.
Publicado: (2016) -
Opposing Functions of the ETS Factor Family Define Shh Spatial Expression in Limb Buds and Underlie Polydactyly
por: Lettice, Laura A., et al.
Publicado: (2012) -
The Conserved Sonic Hedgehog Limb Enhancer Consists of Discrete Functional Elements that Regulate Precise Spatial Expression
por: Lettice, Laura A., et al.
Publicado: (2017)