Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification

Transcription factors (TFs) act within wider regulatory networks to control cell identity and fate. Numerous TFs, including Scl (Tal1) and PU.1 (Spi1), are known regulators of developmental and adult haematopoiesis, but how they act within wider TF networks is still poorly understood. Transcription...

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Detalles Bibliográficos
Autores principales: Wilkinson, Adam C., Kawata, Viviane K. S., Schütte, Judith, Gao, Xuefei, Antoniou, Stella, Baumann, Claudia, Woodhouse, Steven, Hannah, Rebecca, Tanaka, Yosuke, Swiers, Gemma, Moignard, Victoria, Fisher, Jasmin, Hidetoshi, Shimauchi, Tijssen, Marloes R., de Bruijn, Marella F. T. R., Liu, Pentao, Göttgens, Berthold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Techniques and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197694/
https://www.ncbi.nlm.nih.gov/pubmed/25252941
http://dx.doi.org/10.1242/dev.115709

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