Cargando…
ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis
Initially identified in DNA damage repair, ATM-interactor (ATMIN) further functions as a transcriptional regulator of lung morphogenesis. Here we analyse three mouse mutants, Atmin(gpg6/gpg6), Atmin(H210Q/H210Q) and Dynll1(GT/GT), revealing how ATMIN and its transcriptional target dynein light chain...
Autores principales: | Goggolidou, Paraskevi, L. Stevens, Jonathan, Agueci, Francesco, Keynton, Jennifer, Wheway, Gabrielle, Grimes, Daniel T., Patel, Saloni H., Hilton, Helen, Morthorst, Stine K., DiPaolo, Antonella, Williams, Debbie J., Sanderson, Jeremy, Khoronenkova, Svetlana V., Powles-Glover, Nicola, Ermakov, Alexander, Esapa, Chris T., Romero, Rosario, Dianov, Grigory L., Briscoe, James, Johnson, Colin A., Pedersen, Lotte B., Norris, Dominic P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197704/ https://www.ncbi.nlm.nih.gov/pubmed/25294941 http://dx.doi.org/10.1242/dev.107755 |
Ejemplares similares
-
Atmin mediates kidney morphogenesis by modulating Wnt signaling
por: Goggolidou, Paraskevi, et al.
Publicado: (2014) -
Atmin modulates Pkhd1 expression and may mediate Autosomal Recessive Polycystic Kidney Disease (ARPKD) through altered non-canonical Wnt/Planar Cell Polarity (PCP) signalling
por: Richards, Taylor, et al.
Publicado: (2019) -
Regulation of USP7/HAUSP in response to DNA damage: Yet another role for ATM
por: Khoronenkova, Svetlana V., et al.
Publicado: (2012) -
USP7S-dependent inactivation of Mule regulates DNA damage signalling and repair
por: Khoronenkova, Svetlana V., et al.
Publicado: (2013) -
Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation
por: Blake, Sophia M, et al.
Publicado: (2016)