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Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells
BACKGROUND: The TET family of dioxygenases catalyze conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), but their involvement in establishing normal 5mC patterns during mammalian development and their contributions to aberrant control of 5mC during cellular transformation remain...
Autores principales: | Putiri, Emily L, Tiedemann, Rochelle L, Thompson, Joyce J, Liu, Chunsheng, Ho, Thai, Choi, Jeong-Hyeon, Robertson, Keith D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197818/ https://www.ncbi.nlm.nih.gov/pubmed/24958354 http://dx.doi.org/10.1186/gb-2014-15-6-r81 |
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