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Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage

BRCA1 is a breast and ovarian tumor suppressor. Given its numerous incompletely understood functions and the possibility that more exist, we performed complementary systematic screens in search of new BRCA1 protein-interacting partners. New BRCA1 functions and/or a better understanding of existing o...

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Detalles Bibliográficos
Autores principales: Hill, Sarah J., Rolland, Thomas, Adelmant, Guillaume, Xia, Xianfang, Owen, Matthew S., Dricot, Amélie, Zack, Travis I., Sahni, Nidhi, Jacob, Yves, Hao, Tong, McKinney, Kristine M., Clark, Allison P., Reyon, Deepak, Tsai, Shengdar Q., Joung, J. Keith, Beroukhim, Rameen, Marto, Jarrod A., Vidal, Marc, Gaudet, Suzanne, Hill, David E., Livingston, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197947/
https://www.ncbi.nlm.nih.gov/pubmed/25184681
http://dx.doi.org/10.1101/gad.241620.114