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A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36
The dynamic reversible methylation of lysine residues on histone proteins is central to chromatin biology. Key components are demethylase enzymes, which remove methyl moieties from lysine residues. KDM2A, a member of the Jumonji C domain-containing histone lysine demethylase family, specifically tar...
Autores principales: | Cheng, Zhongjun, Cheung, Peggie, Kuo, Alex J., Yukl, Erik T., Wilmot, Carrie M., Gozani, Or, Patel, Dinshaw J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197961/ https://www.ncbi.nlm.nih.gov/pubmed/25128496 http://dx.doi.org/10.1101/gad.246561.114 |
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