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Small intestinal stem cell identity is maintained with functional Paneth cells in heterotopically grafted epithelium onto the colon
To develop stem cell therapy for small intestinal (SI) diseases, it is essential to determine whether SI stem cells in culture retain their tissue regeneration capabilities. By using a heterotopic transplantation approach, we show that cultured murine SI epithelial organoids are able to reconstitute...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197962/ https://www.ncbi.nlm.nih.gov/pubmed/25128495 http://dx.doi.org/10.1101/gad.245233.114 |