Small intestinal stem cell identity is maintained with functional Paneth cells in heterotopically grafted epithelium onto the colon

To develop stem cell therapy for small intestinal (SI) diseases, it is essential to determine whether SI stem cells in culture retain their tissue regeneration capabilities. By using a heterotopic transplantation approach, we show that cultured murine SI epithelial organoids are able to reconstitute...

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Detalles Bibliográficos
Autores principales: Fukuda, Masayoshi, Mizutani, Tomohiro, Mochizuki, Wakana, Matsumoto, Taichi, Nozaki, Kengo, Sakamaki, Yuriko, Ichinose, Shizuko, Okada, Yukinori, Tanaka, Toshihiro, Watanabe, Mamoru, Nakamura, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197962/
https://www.ncbi.nlm.nih.gov/pubmed/25128495
http://dx.doi.org/10.1101/gad.245233.114

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