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The exon junction complex is required for definition and excision of neighboring introns in Drosophila

Splicing of pre-mRNAs results in the deposition of the exon junction complex (EJC) upstream of exon–exon boundaries. The EJC plays crucial post-splicing roles in export, translation, localization, and nonsense-mediated decay of mRNAs. It also aids faithful splicing of pre-mRNAs containing large intr...

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Detalles Bibliográficos
Autores principales: Hayashi, Rippei, Handler, Dominik, Ish-Horowicz, David, Brennecke, Julius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197968/
https://www.ncbi.nlm.nih.gov/pubmed/25081352
http://dx.doi.org/10.1101/gad.245738.114