Cargando…

Identification of a gene regulatory network associated with prion replication

Prions consist of aggregates of abnormal conformers of the cellular prion protein (PrP(C)). They propagate by recruiting host-encoded PrP(C) although the critical interacting proteins and the reasons for the differences in susceptibility of distinct cell lines and populations are unknown. We derived...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marbiah, Masue M, Harvey, Anna, West, Billy T, Louzolo, Anais, Banerjee, Priya, Alden, Jack, Grigoriadis, Anita, Hummerich, Holger, Kan, Ho-Man, Cai, Ying, Bloom, George S, Jat, Parmjit, Collinge, John, Klöhn, Peter-Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198050/ https://www.ncbi.nlm.nih.gov/pubmed/24843046 http://dx.doi.org/10.15252/embj.201387150

Ejemplares similares

In vitro screen of prion disease susceptibility genes using the scrapie cell assay
por: Brown, Craig A., et al.
Publicado: (2014)

Identification of clinical target areas in the brainstem of prion‐infected mice
por: Mirabile, Ilaria, et al.
Publicado: (2015)

Plasmacytoid Dendritic Cells Sequester High Prion Titres at Early Stages of Prion Infection
por: Castro-Seoane, Rocio, et al.
Publicado: (2012)

A high-content neuron imaging assay demonstrates inhibition of prion disease-associated neurotoxicity by an anti-prion protein antibody
por: Reilly, Madeleine, et al.
Publicado: (2022)

A systematic investigation of production of synthetic prions from recombinant prion protein
por: Schmidt, Christian, et al.
Publicado: (2015)

A Copine family member, Cpne8, is a candidate quantitative trait gene for prion disease incubation time in mouse
por: Lloyd, Sarah E., et al.
Publicado: (2009)

Highly infectious prions are not directly neurotoxic
por: Benilova, Iryna, et al.
Publicado: (2020)

Sod1 Deficiency Reduces Incubation Time in Mouse Models of Prion Disease
por: Akhtar, Shaheen, et al.
Publicado: (2013)

Simultaneous expression of MMB-FOXM1 complex components enables efficient bypass of senescence
por: Kumari, Ruchi, et al.
Publicado: (2021)

Activation of Nuclear Factor-kappa B signalling promotes cellular senescence
por: Rovillain, Emilie, et al.
Publicado: (2011)

HECTD2 Is Associated with Susceptibility to Mouse and Human Prion Disease
por: Lloyd, Sarah E., et al.
Publicado: (2009)

Physical, chemical and kinetic factors affecting prion infectivity
por: Properzi, Francesca, et al.
Publicado: (2016)

A call for caution in analysing mammalian co-transfection experiments and implications of resource competition in data misinterpretation
por: Di Blasi, Roberto, et al.
Publicado: (2021)

Polymer Encapsulation of Bacterial Biosensors Enables Coculture with Mammalian Cells
por: Moya-Ramírez, Ignacio, et al.
Publicado: (2022)

Identification of differentially expressed sense and antisense transcript pairs in breast epithelial tissues
por: Grigoriadis, Anita, et al.
Publicado: (2009)

Deciphering the role of Nuclear Factor-κB in cellular senescence
por: Vaughan, Simon, et al.
Publicado: (2011)

Mechanisms of Cellular Senescence: Cell Cycle Arrest and Senescence Associated Secretory Phenotype
por: Kumari, Ruchi, et al.
Publicado: (2021)

Genetics of prion diseases
por: Lloyd, Sarah E, et al.
Publicado: (2013)

Resource-aware construct design in mammalian cells
por: Di Blasi, Roberto, et al.
Publicado: (2023)

Molecular pathology of human prion disease
por: Wadsworth, Jonathan D. F., et al.
Publicado: (2010)

Regulation of p53 and Rb Links the Alternative NF-κB Pathway to EZH2 Expression and Cell Senescence
por: Iannetti, Alessio, et al.
Publicado: (2014)

Rapid cell-surface prion protein conversion revealed using a novel cell system
por: Goold, R., et al.
Publicado: (2011)

Studies on Prion Replication in Spleen
por: Raeber, Alex J., et al.
Publicado: (2001)

Prion replication environment defines the fate of prion strain adaptation
por: Katorcha, Elizaveta, et al.
Publicado: (2018)

Preserving prion strain identity upon replication of prions in vitro using recombinant prion protein
por: Makarava, Natallia, et al.
Publicado: (2018)

Neurotoxic Antibodies against the Prion Protein Do Not Trigger Prion Replication
por: Frontzek, Karl, et al.
Publicado: (2016)

Friend or foe: emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence
por: Mowla, Sophia N, et al.
Publicado: (2013)

Bank vole prion protein extends the use of RT-QuIC assays to detect prions in a range of inherited prion diseases
por: Mok, Tze How, et al.
Publicado: (2021)

When Passive Feels Active - Delusion-Proneness Alters Self-Recognition in the Moving Rubber Hand Illusion
por: Louzolo, Anaïs, et al.
Publicado: (2015)

Cellular Aspects of Prion Replication In Vitro
por: Grassmann, Andrea, et al.
Publicado: (2013)

In vitro replication highlights the mutability of prions
por: Vanni, Ilaria, et al.
Publicado: (2014)

Correction to: preserving prion strain identity upon replication of prions in vitro using recombinant prion protein
por: Makarava, Natallia, et al.
Publicado: (2018)

Prion Uptake in the Gut: Identification of the First Uptake and Replication Sites
por: Kujala, Pekka, et al.
Publicado: (2011)

Direct Observation of Competing Prion Protein Fibril Populations with Distinct Structures and Kinetics
por: Sun, Yuanzi, et al.
Publicado: (2023)

Sialylation of the prion protein glycans controls prion replication rate and glycoform ratio
por: Katorcha, Elizaveta, et al.
Publicado: (2015)

Contrasting Effects of Two Lipid Cofactors of Prion Replication on the Conformation of the Prion Protein
por: Srivastava, Saurabh, et al.
Publicado: (2015)

Cellular senescence and aging: the role of B-MYB
por: Mowla, Sophia N, et al.
Publicado: (2014)

Shadoo (Sprn) and prion disease incubation time in mice
por: Lloyd, Sarah E., et al.
Publicado: (2009)

A New Cell Model for Investigating Prion Strain Selection and Adaptation
por: Philiastides, Alexandra, et al.
Publicado: (2019)

A standardized comparison of commercially available prion decontamination reagents using the Standard Steel-Binding Assay
por: Edgeworth, Julie Ann, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_0adh5mm5qgq0unncpd51sc1sk7