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Rationally Manipulating Aptamer Binding Affinities in a Stem-Loop Molecular Beacon
[Image: see text] Single-stranded DNA sequences that are highly specific for a target ligand are called aptamers. While the incorporation of aptamer sequences into stem-loop molecular beacons has become an essential tool in optical biosensors, the design principles that determine the magnitude of bi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198099/ https://www.ncbi.nlm.nih.gov/pubmed/25170558 http://dx.doi.org/10.1021/bc500286r |